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Truncated C-terminus of fibrillin-1 induces Marfanoid-progeroid-lipodystrophy (MPL) syndrome in rabbit

Various clinical differences have been observed between patients with the FBN1 gene mutation and those with the classical Marfan phenotype. Although FBN1 knockout (KO) or dominant-negative mutant mice are widely used as an animal model for Marfan syndrome (MFS), these mice cannot recapitulate the ge...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Dis Model Mech
Main Authors: Chen, Mao, Yao, Bing, Yang, Qiangbing, Deng, Jichao, Song, Yuning, Sui, Tingting, Zhou, Lina, Yao, HaoBing, Xu, Yuanyuan, Ouyang, Hongsheng, Pang, Daxin, Li, Zhanjun, Lai, Liangxue
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists Ltd 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963856/
https://ncbi.nlm.nih.gov/pubmed/29666143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031542
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