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Marfanoid–progeroid–lipodystrophy syndrome: a newly recognized fibrillinopathy

We review six previous reports between 2000 and 2014 of seven unrelated patients with mutations in the FBN1 gene affecting function. All mutations occurred in exon 64 of the FBN1 gene. A distinctive phenotype consisting of partial manifestations of Marfan syndrome, a progeroid facial appearance, and...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Passarge, Eberhard, Robinson, Peter N, Graul-Neumann, Luitgard M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989216/
https://ncbi.nlm.nih.gov/pubmed/26860060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.6
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