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Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1

The Wnt/β-catenin pathway controls a variety of cellular behaviors, aberrant activation of which are associated with tumor progression in several types of cancer. The same cellular behaviors are also affected by the mechanical properties of the extracellular matrix (ECM) substratum, which induces si...

詳細記述

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書誌詳細
出版年:J Cell Sci
主要な著者: Han, Siyang, Pang, Mei-Fong, Nelson, Celeste M.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963841/
https://ncbi.nlm.nih.gov/pubmed/29588395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.210476
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