SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression

Acute lymphoblastic leukemia (ALL) is associated with significant morbidity and mortality, necessitating further improvements in diagnosis and therapy. Targeted therapies directed against chromatin regulators are emerging as promising approaches in preclinical studies and early clinical trials. Here...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Lin, Chiou-Hong, Wong, Stephen Hon-Kit, Kurzer, Jason H., Schneidawind, Corina, Wei, Michael C., Duque-Afonso, Jesús, Jeong, Johan, Feng, Xuhui, Cleary, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963704/
https://ncbi.nlm.nih.gov/pubmed/29694893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.124
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