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E2A-PBX1 remodels oncogenic signaling networks in B-cell precursor acute lymphoid leukemia

There is limited understanding of how signaling pathways are altered by oncogenic fusion transcription factors that drive leukemogenesis. To address this, we interrogated activated signaling pathways in a comparative analysis of mouse and human leukemias expressing the fusion protein E2A-PBX1, which...

詳細記述

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書誌詳細
出版年:Cancer Res
主要な著者: Duque-Afonso, Jesús, Lin, Chiou-Hong, Han, Kyuho, Wei, Michael C., Feng, Jue, Kurzer, Jason, Schneidawind, Corina, Wong, Stephen Hon-Kit, Bassik, Michael C., Cleary, Michael L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634812/
https://ncbi.nlm.nih.gov/pubmed/27758892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1899
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