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CRMP2 Neurofibromin Interface Drives NF1-related Pain
An understudied symptom of the genetic disorder Neurofibromatosis type 1 (NF1) is chronic idiopathic pain. We used targeted editing of Nf1 in rats to provide direct evidence of a causal relationship between neurofibromin, the protein product of the Nf1 gene, and pain responses. Our study data identi...
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| Veröffentlicht in: | Neuroscience |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963520/ https://ncbi.nlm.nih.gov/pubmed/29655575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.04.002 |
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