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CRMP2 Neurofibromin Interface Drives NF1-related Pain

An understudied symptom of the genetic disorder Neurofibromatosis type 1 (NF1) is chronic idiopathic pain. We used targeted editing of Nf1 in rats to provide direct evidence of a causal relationship between neurofibromin, the protein product of the Nf1 gene, and pain responses. Our study data identi...

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Dades bibliogràfiques
Publicat a:Neuroscience
Autors principals: Moutal, Aubin, Sun, Li, Yang, Xiaofang, Li, Wennan, Cai, Song, Luo, Shizhen, Khanna, Rajesh
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963520/
https://ncbi.nlm.nih.gov/pubmed/29655575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.04.002
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