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Streptonigrin inhibits SENP1 and reduces the protein level of hypoxia-inducible factor 1 (HIF1α) in cells
Streptonigrin (CAS no. 3930-19-6) is a natural product shown to have anti-tumor activities in clinical trials conducted in the 1960s–1970s. However, its use in clinical studies eventually faded, and the molecular mechanisms of streptonigrin anti-tumor effects remain poorly defined. Despite the lack...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963266/ https://ncbi.nlm.nih.gov/pubmed/29481054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00947 |
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