Genetic determinants of circulating GIP and GLP-1 concentrations

The secretion of insulin and glucagon from the pancreas and the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) from the gastrointestinal tract is essential for glucose homeostasis. Several novel treatment strategies for type 2 diabetes (T2D) mimi...

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Pubblicato in:JCI Insight
Autori principali: Almgren, Peter, Lindqvist, Andreas, Krus, Ulrika, Hakaste, Liisa, Ottosson-Laakso, Emilia, Asplund, Olof, Sonestedt, Emily, Prasad, Rashmi B., Laurila, Esa, Orho-Melander, Marju, Melander, Olle, Tuomi, Tiinamaija, Holst, Jens Juul, Nilsson, Peter M., Wierup, Nils, Groop, Leif, Ahlqvist, Emma
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963138/
https://ncbi.nlm.nih.gov/pubmed/29093273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93306
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