Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

OBJECTIVE: The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Tr...

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Autori principali: Lyssenko, Valeriya, Eliasson, Lena, Kotova, Olga, Pilgaard, Kasper, Wierup, Nils, Salehi, Albert, Wendt, Anna, Jonsson, Anna, De Marinis, Yang Z., Berglund, Lisa M., Taneera, Jalal, Balhuizen, Alexander, Hansson, Ola, Osmark, Peter, Dunér, Pontus, Brøns, Charlotte, Stančáková, Alena, Kuusisto, Johanna, Bugliani, Marco, Saxena, Richa, Ahlqvist, Emma, Kieffer, Timothy J., Tuomi, Tiinamaija, Isomaa, Bo, Melander, Olle, Sonestedt, Emily, Orho-Melander, Marju, Nilsson, Peter, Bonetti, Sara, Bonadonna, Riccardo, Miccoli, Roberto, DelPrato, Stefano, Marchetti, Piero, Madsbad, Sten, Poulsen, Pernille, Vaag, Allan, Laakso, Markku, Gomez, Maria F., Groop, Leif
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2011
Soggetti:
Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161325/
https://ncbi.nlm.nih.gov/pubmed/21810601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1532
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