Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

OBJECTIVE: The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Tr...

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主要な著者: Lyssenko, Valeriya, Eliasson, Lena, Kotova, Olga, Pilgaard, Kasper, Wierup, Nils, Salehi, Albert, Wendt, Anna, Jonsson, Anna, De Marinis, Yang Z., Berglund, Lisa M., Taneera, Jalal, Balhuizen, Alexander, Hansson, Ola, Osmark, Peter, Dunér, Pontus, Brøns, Charlotte, Stančáková, Alena, Kuusisto, Johanna, Bugliani, Marco, Saxena, Richa, Ahlqvist, Emma, Kieffer, Timothy J., Tuomi, Tiinamaija, Isomaa, Bo, Melander, Olle, Sonestedt, Emily, Orho-Melander, Marju, Nilsson, Peter, Bonetti, Sara, Bonadonna, Riccardo, Miccoli, Roberto, DelPrato, Stefano, Marchetti, Piero, Madsbad, Sten, Poulsen, Pernille, Vaag, Allan, Laakso, Markku, Gomez, Maria F., Groop, Leif
フォーマット: Artigo
言語:Inglês
出版事項: American Diabetes Association 2011
主題:
Genetics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161325/
https://ncbi.nlm.nih.gov/pubmed/21810601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1532
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