Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

OBJECTIVE: The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Tr...

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Main Authors: Lyssenko, Valeriya, Eliasson, Lena, Kotova, Olga, Pilgaard, Kasper, Wierup, Nils, Salehi, Albert, Wendt, Anna, Jonsson, Anna, De Marinis, Yang Z., Berglund, Lisa M., Taneera, Jalal, Balhuizen, Alexander, Hansson, Ola, Osmark, Peter, Dunér, Pontus, Brøns, Charlotte, Stančáková, Alena, Kuusisto, Johanna, Bugliani, Marco, Saxena, Richa, Ahlqvist, Emma, Kieffer, Timothy J., Tuomi, Tiinamaija, Isomaa, Bo, Melander, Olle, Sonestedt, Emily, Orho-Melander, Marju, Nilsson, Peter, Bonetti, Sara, Bonadonna, Riccardo, Miccoli, Roberto, DelPrato, Stefano, Marchetti, Piero, Madsbad, Sten, Poulsen, Pernille, Vaag, Allan, Laakso, Markku, Gomez, Maria F., Groop, Leif
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2011
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161325/
https://ncbi.nlm.nih.gov/pubmed/21810601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1532
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