Potential role of Plasmodium falciparum exported protein 1 in the chloroquine mode of action

In the human malaria parasite Plasmodium falciparum, membrane glutathione S-transferases (GST) have recently emerged as potential cellular detoxifying units and as drug target candidates with the artemisinin (ART) class of antimalarials inhibiting their activity at single-digit nanomolar potency whe...

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Vydáno v:Int J Parasitol Drugs Drug Resist
Hlavní autoři: Lisewski, Andreas Martin, Quiros, Joel Patrick, Mittal, Monica, Putluri, Nagireddy, Sreekumar, Arun, Haeggström, Jesper Z., Lichtarge, Olivier
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963095/
https://ncbi.nlm.nih.gov/pubmed/29324251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.12.003
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