Plasmodium falciparum chloroquine resistance transporter is a H(+)-coupled polyspecific nutrient and drug exporter

Extrusion of chloroquine (CQ) from digestive vacuoles through the Plasmodium falciparum CQ resistance transporter (PfCRT) is essential to establish CQ resistance of the malaria parasite. However, the physiological relevance of PfCRT and how CQ-resistant PfCRT gains the ability to transport CQ remain...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Juge, Narinobu, Moriyama, Sawako, Miyaji, Takaaki, Kawakami, Mamiyo, Iwai, Haruka, Fukui, Tomoya, Nelson, Nathan, Omote, Hiroshi, Moriyama, Yoshinori
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371956/
https://ncbi.nlm.nih.gov/pubmed/25733858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417102112
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