Deep Sequencing Revealed a CpG Methylation Pattern Associated With ALDH1L1 Suppression in Breast Cancer

Hypermethylation of promoter CpG islands is generally recognized epigenetic mechanism responsible for gene silencing in cancer. However, molecular details on how this epigenetic mark triggers the process of gene downregulation are still elusive. Here, we used deep bisulfite sequencing and qPCR analy...

詳細記述

保存先:
書誌詳細
出版年:Front Genet
主要な著者: Beniaminov, Artemy D., Puzanov, Grigory A., Krasnov, George S., Kaluzhny, Dmitry N., Kazubskaya, Tatiana P., Braga, Eleonora A., Kudryavtseva, Anna V., Melnikova, Nataliya V., Dmitriev, Alexey A.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018
主題:
Genetics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962711/
https://ncbi.nlm.nih.gov/pubmed/29868117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00169
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