SV-BR-1-GM, a Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses an Immune Signature and Directly Activates CD4(+) T Lymphocytes

Targeted cancer immunotherapy with irradiated, granulocyte–macrophage colony-stimulating factor (GM-CSF)-secreting, allogeneic cancer cell lines has been an effective approach to reduce tumor burden in several patients. It is generally assumed that to be effective, these cell lines need to express i...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lacher, Markus D., Bauer, Gerhard, Fury, Brian, Graeve, Sanne, Fledderman, Emily L., Petrie, Tye D., Coleal-Bergum, Dane P., Hackett, Tia, Perotti, Nicholas H., Kong, Ying Y., Kwok, William W., Wagner, Joseph P., Wiseman, Charles L., Williams, William V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962696/
https://ncbi.nlm.nih.gov/pubmed/29867922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00776
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