Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer

The clinical application of GX1, an optimal gastric cancer (GC) targeting peptide, is greatly limited because its receptor in the GC vasculature is unknown. In this study, we screened the candidate receptor of GX1, transglutaminase-2(TGM2), by co-immunoprecipitation (co-IP) combined with mass spectr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Death Dis
Main Authors: Lei, Zhijie, Chai, Na, Tian, Miaomiao, Zhang, Ying, Wang, Guodong, Liu, Jian, Tian, Zuhong, Yi, Xiaofang, Chen, Di, Li, Xiaowei, Yu, Pengfei, Hu, Hao, Xu, Bing, Jian, Chao, Bian, Zhenyuan, Guo, Hao, Wang, Jinpeng, Peng, Shiming, Nie, Yongzhan, Huang, Niu, Hu, Sijun, Wu, Kaichun
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962530/
https://ncbi.nlm.nih.gov/pubmed/29785022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0594-x
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