Loss of Barx1 promotes hepatocellular carcinoma metastasis through up-regulating MGAT5 and MMP9 expression and indicates poor prognosis

Metastasis is the major dominant reason for poor prognosis of hepatocellular carcinoma (HCC) after surgical treatment. However, the molecular mechanism of metastasis has not been well characterzied. Here, we report a novel function of Barx homeobox1 (Barx1) in inhibiting HCC invasion and metastasis....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Guodong, Liu, Jian, Cai, Yi, Chen, Jie, Xie, Wenbing, Kong, Xiangqian, Huang, Wenjie, Guo, Hao, Zhao, Xiaodi, Lu, Yuanyuan, Niu, Lu, Li, Xiaowei, Zhang, Haijia, Lei, Chao, Lei, Zhijie, Yin, Jipeng, Hu, Hao, Yu, Fan, Nie, Yongzhan, Xia, Limin, Wu, Kaichun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641096/
https://ncbi.nlm.nih.gov/pubmed/29069753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18288
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