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Loss of Barx1 promotes hepatocellular carcinoma metastasis through up-regulating MGAT5 and MMP9 expression and indicates poor prognosis

Metastasis is the major dominant reason for poor prognosis of hepatocellular carcinoma (HCC) after surgical treatment. However, the molecular mechanism of metastasis has not been well characterzied. Here, we report a novel function of Barx homeobox1 (Barx1) in inhibiting HCC invasion and metastasis....

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Wang, Guodong, Liu, Jian, Cai, Yi, Chen, Jie, Xie, Wenbing, Kong, Xiangqian, Huang, Wenjie, Guo, Hao, Zhao, Xiaodi, Lu, Yuanyuan, Niu, Lu, Li, Xiaowei, Zhang, Haijia, Lei, Chao, Lei, Zhijie, Yin, Jipeng, Hu, Hao, Yu, Fan, Nie, Yongzhan, Xia, Limin, Wu, Kaichun
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641096/
https://ncbi.nlm.nih.gov/pubmed/29069753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18288
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