Loss of Barx1 promotes hepatocellular carcinoma metastasis through up-regulating MGAT5 and MMP9 expression and indicates poor prognosis

Metastasis is the major dominant reason for poor prognosis of hepatocellular carcinoma (HCC) after surgical treatment. However, the molecular mechanism of metastasis has not been well characterzied. Here, we report a novel function of Barx homeobox1 (Barx1) in inhibiting HCC invasion and metastasis....

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Veröffentlicht in:Oncotarget
Hauptverfasser: Wang, Guodong, Liu, Jian, Cai, Yi, Chen, Jie, Xie, Wenbing, Kong, Xiangqian, Huang, Wenjie, Guo, Hao, Zhao, Xiaodi, Lu, Yuanyuan, Niu, Lu, Li, Xiaowei, Zhang, Haijia, Lei, Chao, Lei, Zhijie, Yin, Jipeng, Hu, Hao, Yu, Fan, Nie, Yongzhan, Xia, Limin, Wu, Kaichun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641096/
https://ncbi.nlm.nih.gov/pubmed/29069753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18288
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