Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancer

BACKGROUND: Loss of cell-cell adhesion is important for the development of cancer invasion and metastasis. Vinculin, a key adhesion-related protein, can affect metastasis and prognosis in several tumours. Here, we determined the biological roles of vinculin in the metastasis of colorectal cancer (CR...

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Vydáno v:Mol Cancer
Hlavní autoři: Li, Ting, Guo, Hanqing, Song, Ying, Zhao, Xiaodi, Shi, Yongquan, Lu, Yuanyuan, Hu, Sijun, Nie, Yongzhan, Fan, Daiming, Wu, Kaichun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320448/
https://ncbi.nlm.nih.gov/pubmed/25496021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-263
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