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Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells

Increased protein translation in cells and various factors in the tumor microenvironment can induce endoplasmic reticulum (ER) stress, which initiates the unfolded protein response (UPR). We have previously reported that factors released from cancer cells mounting a UPR induce a de novo UPR in bone...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Rodvold, Jeffrey J., Chiu, Kevin T., Hiramatsu, Nobuhiko, Nussbacher, Julia K., Galimberti, Valentina, Mahadevan, Navin R., Willert, Karl, Lin, Jonathan H., Zanetti, Maurizio
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962022/
https://ncbi.nlm.nih.gov/pubmed/28588081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aah7177
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