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Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells

Increased protein translation in cells and various factors in the tumor microenvironment can induce endoplasmic reticulum (ER) stress, which initiates the unfolded protein response (UPR). We have previously reported that factors released from cancer cells mounting a UPR induce a de novo UPR in bone...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Rodvold, Jeffrey J., Chiu, Kevin T., Hiramatsu, Nobuhiko, Nussbacher, Julia K., Galimberti, Valentina, Mahadevan, Navin R., Willert, Karl, Lin, Jonathan H., Zanetti, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962022/
https://ncbi.nlm.nih.gov/pubmed/28588081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aah7177
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