Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function

During ontogeny, fetal liver (FL) acts as a major site for hematopoietic stem cell (HSC) maturation and expansion, whereas HSCs in the adult bone marrow (ABM) are largely quiescent. HSCs in the FL possess faster repopulation capacity as compared with ABM HSCs. However, the molecular mechanism regula...

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Pubblicato in:Stem Cells Dev
Autori principali: Manesia, Javed K., Franch, Monica, Tabas-Madrid, Daniel, Nogales-Cadenas, Ruben, Vanwelden, Thomas, Van Den Bosch, Elisa, Xu, Zhuofei, Pascual-Montano, Alberto, Khurana, Satish, Verfaillie, Catherine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961932/
https://ncbi.nlm.nih.gov/pubmed/27958775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0294
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