Spontaneous mutations in CYC8 and MIG1 suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK

Chronologically aging yeast cells are prone to adaptive regrowth, whereby mutants with a survival advantage spontaneously appear and re-enter the cell cycle in stationary phase cultures. Adaptive regrowth is especially noticeable with short-lived strains, including those defective for SNF1, the homo...

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Udgivet i:Microb Cell
Main Authors: Maqani, Nazif, Fine, Ryan D., Shahid, Mehreen, Li, Mingguang, Enriquez-Hesles, Elisa, Smith, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: Shared Science Publishers OG 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961917/
https://ncbi.nlm.nih.gov/pubmed/29796388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2018.05.630
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