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Foxo1 and Foxp1 play opposing roles in regulating the differentiation and antitumor activity of T(H)9 cells programmed by IL-7

Tumor-specific CD4(+) T helper 9 (T(H)9) cells, so-called because of their production of the cytokine interleukin-9 (IL-9), are a powerful effector T cell subset for cancer immunotherapy. We found that pretreatment of naïve CD4(+) T cells with IL-7 further enhanced their differentiation into T(H)9 c...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Signal
Main Authors: Bi, Enguang, Ma, Xingzhe, Lu, Yong, Yang, Maojie, Wang, Qiang, Xue, Gang, Qian, Jianfei, Wang, Siqing, Yi, Qing
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961737/
https://ncbi.nlm.nih.gov/pubmed/29018172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aak9741
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