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Non-Covalent Assembly Method that Simultaneously Endows a Liposome Surface with Targeting Ligands, Protective PEG Chains, and Deep-Red Fluorescence Reporter Groups

A new self-assembly method is used to rapidly functionalize the surface of liposomes without perturbing the membrane integrity or causing leakage of the aqueous contents. The key molecule is a cholesterol-squaraine-PEG conjugate with three important structural elements: a cholesterol membrane anchor...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Shaw, Scott K., Liu, Wenqi, Brennan, Seamus P., de Lourdes Betancourt-Mendiola, María, Smith, Bradley D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961722/
https://ncbi.nlm.nih.gov/pubmed/28736857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201702649
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