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Peptide ligand and PEG-mediated long-circulating liposome targeted to FGFR overexpressing tumor in vivo

BACKGROUND AND METHODS: Paclitaxel, a widely used antitumor agent, has limited clinical application due to its hydrophobicity and systemic toxicity. To achieve sustained and targeted delivery of paclitaxel to tumor sites, liposomes composed of egg phosphatidylcholine, cholesterol, and distearolyphos...

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Detalhes bibliográficos
Main Authors: Cai, Lulu, Wang, Xianhuo, Wang, Wenwen, Qiu, Neng, Wen, Jiaolin, Duan, Xingmei, Li, Xia, Chen, Xiang, Yang, Li, Qian, Zhiyong, Wei, Yuquan, Chen, Lijuan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423151/
https://ncbi.nlm.nih.gov/pubmed/22923988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32817
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