Peptide ligand and PEG-mediated long-circulating liposome targeted to FGFR overexpressing tumor in vivo

BACKGROUND AND METHODS: Paclitaxel, a widely used antitumor agent, has limited clinical application due to its hydrophobicity and systemic toxicity. To achieve sustained and targeted delivery of paclitaxel to tumor sites, liposomes composed of egg phosphatidylcholine, cholesterol, and distearolyphos...

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Bibliographische Detailangaben
Hauptverfasser: Cai, Lulu, Wang, Xianhuo, Wang, Wenwen, Qiu, Neng, Wen, Jiaolin, Duan, Xingmei, Li, Xia, Chen, Xiang, Yang, Li, Qian, Zhiyong, Wei, Yuquan, Chen, Lijuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2012
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423151/
https://ncbi.nlm.nih.gov/pubmed/22923988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32817
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