CMS-dependent prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer

BACKGROUND: The prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer (CRC) varies with microsatellite instability (MSI) status. The gene expression–based consensus molecular subtypes (CMSs) of CRC define molecularly and clinically distinct subgroups, and represent a novel...

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Bibliographic Details
Published in:Ann Oncol
Main Authors: Smeby, J, Sveen, A, Merok, M A, Danielsen, S A, Eilertsen, I A, Guren, M G, Dienstmann, R, Nesbakken, A, Lothe, R A
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961317/
https://ncbi.nlm.nih.gov/pubmed/29518181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy085
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