CMS-dependent prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer

BACKGROUND: The prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer (CRC) varies with microsatellite instability (MSI) status. The gene expression–based consensus molecular subtypes (CMSs) of CRC define molecularly and clinically distinct subgroups, and represent a novel...

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Publicat a:Ann Oncol
Autors principals: Smeby, J, Sveen, A, Merok, M A, Danielsen, S A, Eilertsen, I A, Guren, M G, Dienstmann, R, Nesbakken, A, Lothe, R A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961317/
https://ncbi.nlm.nih.gov/pubmed/29518181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy085
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