CMS-dependent prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer

BACKGROUND: The prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer (CRC) varies with microsatellite instability (MSI) status. The gene expression–based consensus molecular subtypes (CMSs) of CRC define molecularly and clinically distinct subgroups, and represent a novel...

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Bibliografiske detaljer
Udgivet i:Ann Oncol
Main Authors: Smeby, J, Sveen, A, Merok, M A, Danielsen, S A, Eilertsen, I A, Guren, M G, Dienstmann, R, Nesbakken, A, Lothe, R A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961317/
https://ncbi.nlm.nih.gov/pubmed/29518181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy085
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