CMS-dependent prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer

BACKGROUND: The prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer (CRC) varies with microsatellite instability (MSI) status. The gene expression–based consensus molecular subtypes (CMSs) of CRC define molecularly and clinically distinct subgroups, and represent a novel...

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Detalles Bibliográficos
Publicado en:Ann Oncol
Main Authors: Smeby, J, Sveen, A, Merok, M A, Danielsen, S A, Eilertsen, I A, Guren, M G, Dienstmann, R, Nesbakken, A, Lothe, R A
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961317/
https://ncbi.nlm.nih.gov/pubmed/29518181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy085
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