Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension

Telomere maintenance protects the cell against genome instability and senescence. Accelerated telomere attrition is a characteristic of premature aging syndromes including Dyskeratosis congenita (DC). Mutations in hRTEL1 are associated with a severe form of DC called Hoyeraal-Hreidarsson syndrome (H...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Porreca, Rosa M, Glousker, Galina, Awad, Aya, Matilla Fernandez, Maria I, Gibaud, Anne, Naucke, Christian, Cohen, Scott B, Bryan, Tracy M, Tzfati, Yehuda, Draskovic, Irena, Londoño-Vallejo, Arturo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961080/
https://ncbi.nlm.nih.gov/pubmed/29522136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky173
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak