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Role of ROS in Aβ42 Mediated Activation of Cerebral Endothelial Cells

INTRODUCTION: There is substantial evidence that the deposition of aggregated amyloid-beta peptide (Aβ) in brain parenchyma and brain vessels is the main cause of neuronal dysfunction and death in Alzheimer’s disease (AD). Aβ exhibits multiple cytotoxic effects on neurons and glial cells and causes...

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Bibliographische Detailangaben
Veröffentlicht in:Cent Asian J Glob Health
Hauptverfasser: Tsoy, Andrey, Umbayev, Bauyrzhan, Shalakhmetova, Tamara, Askarova, Sholpan
Format: Artigo
Sprache:Inglês
Veröffentlicht: University Library System, University of Pittsburgh 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960947/
https://ncbi.nlm.nih.gov/pubmed/29805908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5195/cajgh.2014.179
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