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Role of ROS in Aβ42 Mediated Activation of Cerebral Endothelial Cells

INTRODUCTION: There is substantial evidence that the deposition of aggregated amyloid-beta peptide (Aβ) in brain parenchyma and brain vessels is the main cause of neuronal dysfunction and death in Alzheimer’s disease (AD). Aβ exhibits multiple cytotoxic effects on neurons and glial cells and causes...

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Detalhes bibliográficos
Publicado no:Cent Asian J Glob Health
Main Authors: Tsoy, Andrey, Umbayev, Bauyrzhan, Shalakhmetova, Tamara, Askarova, Sholpan
Formato: Artigo
Idioma:Inglês
Publicado em: University Library System, University of Pittsburgh 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960947/
https://ncbi.nlm.nih.gov/pubmed/29805908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5195/cajgh.2014.179
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