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Role of ROS in Aβ42 Mediated Activation of Cerebral Endothelial Cells

INTRODUCTION: There is substantial evidence that the deposition of aggregated amyloid-beta peptide (Aβ) in brain parenchyma and brain vessels is the main cause of neuronal dysfunction and death in Alzheimer’s disease (AD). Aβ exhibits multiple cytotoxic effects on neurons and glial cells and causes...

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Bibliografske podrobnosti
izdano v:Cent Asian J Glob Health
Main Authors: Tsoy, Andrey, Umbayev, Bauyrzhan, Shalakhmetova, Tamara, Askarova, Sholpan
Format: Artigo
Jezik:Inglês
Izdano: University Library System, University of Pittsburgh 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960947/
https://ncbi.nlm.nih.gov/pubmed/29805908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5195/cajgh.2014.179
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