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Role of ROS in Aβ42 Mediated Activation of Cerebral Endothelial Cells

INTRODUCTION: There is substantial evidence that the deposition of aggregated amyloid-beta peptide (Aβ) in brain parenchyma and brain vessels is the main cause of neuronal dysfunction and death in Alzheimer’s disease (AD). Aβ exhibits multiple cytotoxic effects on neurons and glial cells and causes...

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Dettagli Bibliografici
Pubblicato in:Cent Asian J Glob Health
Autori principali: Tsoy, Andrey, Umbayev, Bauyrzhan, Shalakhmetova, Tamara, Askarova, Sholpan
Natura: Artigo
Lingua:Inglês
Pubblicazione: University Library System, University of Pittsburgh 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960947/
https://ncbi.nlm.nih.gov/pubmed/29805908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5195/cajgh.2014.179
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