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The transition state structure for binding between TAZ1 of CBP and the disordered Hif-1α CAD

Intrinsically disordered proteins (IDPs) are common in eukaryotes. However, relatively few experimental studies have addressed the nature of the rate-limiting transition state for the coupled binding and folding reactions involving IDPs. By using site-directed mutagenesis in combination with kinetic...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lindström, Ida, Andersson, Eva, Dogan, Jakob
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959852/
https://ncbi.nlm.nih.gov/pubmed/29777197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26213-x
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