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Cis- and trans-modifiers of repeat expansions: Blending model systems with human genetics
Over thirty hereditary diseases are caused by the expansion of microsatellite repeats. The length of the expandable repeat is the main hereditary determinant of these disorders. They are also affected by numerous genomic variants that are nearby (cis) and physically separated from (trans) the repeti...
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| Publicado no: | Trends Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5959756/ https://ncbi.nlm.nih.gov/pubmed/29567336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2018.02.005 |
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