A comprehensive Pan-Cancer molecular study of gynecologic and breast cancers

We analyzed molecular data on 2,579 TCGA tumors of four gynecological types plus breast. Our aims were to identify shared and unique molecular features, clinically significant subtypes, and potential therapeutic targets. We found 61 somatic copy number alterations (SCNAs) and 46 significantly mutate...

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Veröffentlicht in:Cancer Cell
Hauptverfasser: Berger, Ashton C., Korkut, Anil, Kanchi, Rupa S., Hegde, Apurva M., Lenoir, Walter, Liu, Wenbin, Liu, Yuexin, Fan, Huihui, Shen, Hui, Ravikumar, Visweswaran, Rao, Arvind, Schultz, Andre, Li, Xubin, Baggerly, Keith A., Manyam, Ganiraju, Sumazin, Pavel, Williams, Cecilia, Mestagh, Pieter, Gunaratne, Preethi H., Yau, Christina, Bowlby, Reanne, Tiezzi, Daniel G., Wang, Chen, Cherniack, Andrew D., Priedigkeit, Nolan, Edwards, Robert P., Oesterreich, Steffi, Liu, Liang, Song, Qianqian, Burk, Robert D., Stetson, Lindsay, Pitt, Jason, Winterhoff, Boris, Godwin, Andrew K., Kuderer, Nicole M., Rader, Janet S., Zuna, Rosemary E., Sood, Anil K., Lazar, Alexander J., Ojesina, Akinyemi I., Weinstein, John N., Mills, Gordon B., Levine, Douglas A., Akbani, Rehan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959730/
https://ncbi.nlm.nih.gov/pubmed/29622464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.014
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