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Integrated Molecular Characterization of Uterine Carcinosarcoma

We performed genomic, epigenomic, transcriptomic and proteomic characterizations of uterine carcinosarcomas (UCSs). Cohort samples had extensive copy number alterations and highly recurrent somatic mutations. Frequent mutations were found in TP53, PTEN, PIK3CA, PPP2R1A, FBXW7 and KRAS, similar to en...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Cherniack, Andrew, Shen, Hui, Walter, Vonn, Stewart, Chip, Murray, Bradley, Bowlby, Reanne, Hu, Xin, Ling, Shiyun, Soslow, Robert A., Broaddus, Russell R., Zuna, Rosemary E., Robertson, Gordon, Laird, Peter W., Kucherlapati, Raju, Mills, Gordon B, Weinstein, John N, Zhang, Jiashan, Akbani, Rehan, Levine, Douglas A
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599133/
https://ncbi.nlm.nih.gov/pubmed/28292439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.02.010
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