Integrated Molecular Characterization of Uterine Carcinosarcoma

We performed genomic, epigenomic, transcriptomic and proteomic characterizations of uterine carcinosarcomas (UCSs). Cohort samples had extensive copy number alterations and highly recurrent somatic mutations. Frequent mutations were found in TP53, PTEN, PIK3CA, PPP2R1A, FBXW7 and KRAS, similar to en...

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Publié dans:Cancer Cell
Auteurs principaux: Cherniack, Andrew, Shen, Hui, Walter, Vonn, Stewart, Chip, Murray, Bradley, Bowlby, Reanne, Hu, Xin, Ling, Shiyun, Soslow, Robert A., Broaddus, Russell R., Zuna, Rosemary E., Robertson, Gordon, Laird, Peter W., Kucherlapati, Raju, Mills, Gordon B, Weinstein, John N, Zhang, Jiashan, Akbani, Rehan, Levine, Douglas A
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599133/
https://ncbi.nlm.nih.gov/pubmed/28292439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.02.010
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