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Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield

Solid tumors are able to establish and sustain an immune suppressive microenvironment, which prevents the infiltration of cytotoxic effector immune cells into the tumor bed. We showed that genetic targeting of the macroautophagy/autophagy gene Becn1/Beclin1 in B16-F10 tumors inhibits their growth by...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Noman, Muhammad Zaeem, Berchem, Guy, Janji, Bassam
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959322/
https://ncbi.nlm.nih.gov/pubmed/29368981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1427398
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