Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

Recent studies demonstrated that autophagy is an important regulator of innate immune response. However, the mechanism by which autophagy regulates natural killer (NK) cell-mediated antitumor immune responses remains elusive. Here, we demonstrate that hypoxia impairs breast cancer cell susceptibilit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Baginska, Joanna, Viry, Elodie, Berchem, Guy, Poli, Aurélie, Noman, Muhammad Zaeem, van Moer, Kris, Medves, Sandrine, Zimmer, Jacques, Oudin, Anaïs, Niclou, Simone P., Bleackley, R. Chris, Goping, Ing Swie, Chouaib, Salem, Janji, Bassam
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808626/
https://ncbi.nlm.nih.gov/pubmed/24101526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304790110
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge