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Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield

Solid tumors are able to establish and sustain an immune suppressive microenvironment, which prevents the infiltration of cytotoxic effector immune cells into the tumor bed. We showed that genetic targeting of the macroautophagy/autophagy gene Becn1/Beclin1 in B16-F10 tumors inhibits their growth by...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Noman, Muhammad Zaeem, Berchem, Guy, Janji, Bassam
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959322/
https://ncbi.nlm.nih.gov/pubmed/29368981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1427398
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