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SPHK1 promotes metastasis of thyroid carcinoma through activation of the S1P/S1PR3/Notch signaling pathway

Thyroid carcinoma is characterized by an aggressive behavior, lack of effective targeted therapies and a high rate of relapse. Sphingosine kinase 1 (SPHK1) has been reported to be a critical regulatory factor in the progression of thyroid carcinoma, but the correlation between SPHK1 and clinical pro...

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Bibliografiske detaljer
Udgivet i:Exp Ther Med
Main Authors: Zhao, Zhijing, Ma, Junfeng, Hu, Baoquan, Zhang, Yi, Wang, Shushu
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958638/
https://ncbi.nlm.nih.gov/pubmed/29805524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6054
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