SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway

BACKGROUND: Triple-negative breast cancer (TNBC) features a poor prognosis, which is partially attributed to its high metastatic rate. However, there is no effective target for systemic TNBC therapy due to the absence of estrogen, progesterone, and human epidermal growth factor 2 receptors (ER, PR,...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Shi, Weiwei, Ma, Ding, Cao, Yin, Hu, Lili, Liu, Shuwen, Yan, Dongliang, Zhang, Shan, Zhang, Guang, Wang, Zhongxia, Wu, Junhua, Jiang, Chunping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100449/
https://ncbi.nlm.nih.gov/pubmed/33968977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.598218
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