SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway

BACKGROUND: Triple-negative breast cancer (TNBC) features a poor prognosis, which is partially attributed to its high metastatic rate. However, there is no effective target for systemic TNBC therapy due to the absence of estrogen, progesterone, and human epidermal growth factor 2 receptors (ER, PR,...

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Bibliografski detalji
Izdano u:Front Mol Biosci
Glavni autori: Shi, Weiwei, Ma, Ding, Cao, Yin, Hu, Lili, Liu, Shuwen, Yan, Dongliang, Zhang, Shan, Zhang, Guang, Wang, Zhongxia, Wu, Junhua, Jiang, Chunping
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Molecular Biosciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100449/
https://ncbi.nlm.nih.gov/pubmed/33968977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.598218
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