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Application of Electrochemical Devices to Characterize the Dynamic Actions of Helicases on DNA

Much remains to be understood about the kinetics and thermodynamics of DNA helicase binding and activity. Here, we utilize probe-modified DNA monolayers on multiplexed gold electrodes as a sensitive recognition element and morphologically responsive transducer of helicase–DNA interactions. The elect...

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Bibliografiske detaljer
Udgivet i:Anal Chem
Main Authors: Kahanda, Dimithree, DuPrez, Kevin T., Hilario, Eduardo, McWilliams, Marc A., Wohlgamuth, Chris H., Fan, Li, Slinker, Jason D.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957534/
https://ncbi.nlm.nih.gov/pubmed/29285929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04515
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