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Application of Electrochemical Devices to Characterize the Dynamic Actions of Helicases on DNA

Much remains to be understood about the kinetics and thermodynamics of DNA helicase binding and activity. Here, we utilize probe-modified DNA monolayers on multiplexed gold electrodes as a sensitive recognition element and morphologically responsive transducer of helicase–DNA interactions. The elect...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Kahanda, Dimithree, DuPrez, Kevin T., Hilario, Eduardo, McWilliams, Marc A., Wohlgamuth, Chris H., Fan, Li, Slinker, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957534/
https://ncbi.nlm.nih.gov/pubmed/29285929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b04515
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