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Structural basis of the XPB–Bax1 complex as a dynamic helicase–nuclease machinery for DNA repair

Nucleotide excision repair (NER) is a major DNA repair pathway for a variety of DNA lesions. XPB plays a key role in DNA opening at damage sites and coordinating damage incision by nucleases. XPB is conserved from archaea to human. In archaea, XPB is associated with a nuclease Bax1. Here we report c...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: DuPrez, Kevin, He, Feng, Chen, Zhenhang, Hilario, Eduardo, Fan, Li
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293015/
https://ncbi.nlm.nih.gov/pubmed/32374860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa324
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