Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart

Fibroblasts are a dynamic cell type that achieve selective differentiated states to mediate acute wound healing and long-term tissue remodeling with scarring. With myocardial infarction injury, cardiomyocytes are replaced by secreted extracellular matrix proteins produced by proliferating and differ...

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Vydáno v:J Clin Invest
Hlavní autoři: Fu, Xing, Khalil, Hadi, Kanisicak, Onur, Boyer, Justin G., Vagnozzi, Ronald J., Maliken, Bryan D., Sargent, Michelle A., Prasad, Vikram, Valiente-Alandi, Iñigo, Blaxall, Burns C., Molkentin, Jeffery D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957472/
https://ncbi.nlm.nih.gov/pubmed/29664017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98215
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