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Gata4-Dependent Differentiation of c-Kit(+)–Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart

BACKGROUND: Although c-Kit(+) adult progenitor cells were initially reported to produce new cardiomyocytes in the heart, recent genetic evidence suggests that such events are exceedingly rare. However, to determine if these rare events represent true de novo cardiomyocyte formation, we deleted the n...

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Detalhes bibliográficos
Publicado no:Circulation
Principais autores: Maliken, Bryan D., Kanisicak, Onur, Karch, Jason, Khalil, Hadi, Fu, Xing, Boyer, Justin G., Prasad, Vikram, Zheng, Yi, Molkentin, Jeffery D.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125755/
https://ncbi.nlm.nih.gov/pubmed/29666070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.033703
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