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Pre-clinical activity of targeting the PI3K/Akt/mTOR pathway in Burkitt lymphoma
Though outcomes for pediatric Burkitt lymphoma (BL) have improved significantly in recent decades with intensive multi-agent chemotherapy and the addition of rituximab, chemotherapy resistance remains a significant impediment to cure following relapse. Activation of the PI3K/AKT pathway has been imp...
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| Veröffentlicht in: | Oncotarget |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955151/ https://ncbi.nlm.nih.gov/pubmed/29774105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25072 |
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