BACTEROIDES FRAGILIS TOXIN COORDINATES A PRO-CARCINOGENIC INFLAMMATORY CASCADE VIA TARGETING OF COLONIC EPITHELIAL CELLS

Pro-carcinogenic bacteria have the potential to initiate and/or promote colon cancer, in part via immune mechanisms that are incompletely understood. Using Apc(Min) mice colonized with the human pathobiont enterotoxigenic Bacteroides fragilis (ETBF) as a model of microbial-induced colon tumorigenesi...

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Pubblicato in:Cell Host Microbe
Autori principali: Chung, Liam, Orberg, Erik Thiele, Geis, Abby L., Chan, June L., Fu, Kai, DeStefano Shields, Christina E., Dejea, Christine M., Fathi, Payam, Chen, Jie, Finard, Benjamin B., Tam, Ada J., McAllister, Florencia M., Fan, Hongni, Wu, Xinqun, Ganguly, Sudipto, Lebid, Andriana, Metz, Paul, Van Meerbeke, Sara W., Huso, David L., Wick, Elizabeth C., Pardoll, Drew M., Wan, Fengyi, Wu, Shaoguang, Sears, Cynthia L., Housseau, Franck
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954996/
https://ncbi.nlm.nih.gov/pubmed/29398651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.01.007
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