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Regulatory T cell response to enterotoxigenic Bacteroides fragilis colonization triggers IL-17-dependent colon carcinogenesis

Many epithelial cancers are associated with chronic inflammation. However, the features of inflammation that are pro-carcinogenic are not fully understood. Tregs typically restrain overt inflammatory responses and maintain intestinal immune homeostasis. Their immune suppressive activity can inhibit...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Geis, Abby L., Fan, Hongni, Wu, Xinqun, Wu, Shaoguang, Huso, David L., Wolfe, Jaime L., Sears, Cynthia L., Pardoll, Drew M., Housseau, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592451/
https://ncbi.nlm.nih.gov/pubmed/26201900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0447
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