BACTEROIDES FRAGILIS TOXIN COORDINATES A PRO-CARCINOGENIC INFLAMMATORY CASCADE VIA TARGETING OF COLONIC EPITHELIAL CELLS

Pro-carcinogenic bacteria have the potential to initiate and/or promote colon cancer, in part via immune mechanisms that are incompletely understood. Using Apc(Min) mice colonized with the human pathobiont enterotoxigenic Bacteroides fragilis (ETBF) as a model of microbial-induced colon tumorigenesi...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Chung, Liam, Orberg, Erik Thiele, Geis, Abby L., Chan, June L., Fu, Kai, DeStefano Shields, Christina E., Dejea, Christine M., Fathi, Payam, Chen, Jie, Finard, Benjamin B., Tam, Ada J., McAllister, Florencia M., Fan, Hongni, Wu, Xinqun, Ganguly, Sudipto, Lebid, Andriana, Metz, Paul, Van Meerbeke, Sara W., Huso, David L., Wick, Elizabeth C., Pardoll, Drew M., Wan, Fengyi, Wu, Shaoguang, Sears, Cynthia L., Housseau, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954996/
https://ncbi.nlm.nih.gov/pubmed/29398651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.01.007
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